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Lexington Area Experiences Series of Vehicle Crashes Resulting in Multiple Injuries and One Fatality

Emergency response at vehicle crash scene in Lexington

Lexington, KY, September 15, 2025

News Summary

The Lexington area witnessed several vehicle crashes over the weekend, including a fatal incident on Interstate 64 that resulted in three deaths. Other accidents included injuries from a multi-vehicle crash on Paris Pike, and multiple incidents on Nicholasville Road involving DUI. Investigations are ongoing as authorities assess safety concerns in the region.

Lexington Area Experiences Series of Vehicle Crashes Resulting in Multiple Injuries and One Fatality

Multiple vehicle crashes in the Lexington area over the weekend led to numerous injuries, including one fatal incident on Interstate 64. The incidents have prompted ongoing investigations by local authorities.

Friday’s Fatal Crash on Interstate 64

A severe crash on Interstate 64 occurred late Friday around 7:30 p.m. involving four tractor-trailers and two cars, resulting in the deaths of three individuals. The incident took place near mile marker 61, where smoke and fire were reported at the crash scene. The fatalities included two tractor-trailer drivers and one passenger car occupant. All westbound lanes of I-64 were closed for several hours, with traffic resuming around 7:15 a.m. on Saturday. The causes of the crash are still under investigation by the Lexington Police Department.

Thursday’s Multi-Person Crash at Paris Pike

Earlier in the week, on Thursday before 7:00 p.m., a single-vehicle crash at the intersection of Paris Pike and Iron Works Parkway led to four individuals being taken to the hospital. All occupants were trapped in the vehicle and required extraction by the Lexington Fire Department using the jaws of life. Of the four, two sustained critical injuries, and the investigation regarding this incident is ongoing.

Sunday’s Crash on Russell Cave Road

On Sunday at approximately 4:20 p.m., a single-vehicle crash in the 6100 block of Russell Cave Road resulted in one individual being hospitalized with non-life-threatening injuries. The vehicle went through a fence, and the road was expected to reopen by 6:30 p.m.

Weekend DUI Incident on Nicholasville Road

A separate incident on Nicholasville Road late Saturday night saw a 17-year-old charged with DUI after being involved in two crashes. Police received a call around 11:00 p.m. about a non-injury hit-and-run, followed by another crash involving three vehicles near Canary Road. One person involved in this collision sustained life-threatening injuries while two others had non-life-threatening injuries. The minor was charged with first-degree assault and leaving the scene of an accident, with the Collision Reconstruction Unit continuing the investigation.

Fatal Crash in Lexington County, S.C.

In a separate incident in Lexington County, S.C., a head-on crash on Old Cherokee Road late Saturday around 10:57 p.m. resulted in one fatality. A 2020 Ford SUV crossed off the roadway, hit a mailbox, and collided head-on with a 2016 Infiniti SUV. The driver of the Ford, who was the sole occupant, was pronounced dead at the scene. The driver of the Infiniti sustained injuries and was taken to a nearby hospital for treatment. The South Carolina Highway Patrol is investigating this tragic incident, with further details about the victim to be released by the Lexington County Coroner’s Office.

Summary of Recent Crashes in Lexington Area

The Lexington area has seen a troubling pattern of vehicle crashes recently, with several incidents resulting in injuries and fatalities. The combination of high traffic incidents raises concerns about road safety and driver awareness.

FAQs

What incidents were reported in the Lexington area?

Several crashes occurred, including a fatal multi-vehicle collision on Interstate 64, a crash involving four people hospitalized at Paris Pike, a single-vehicle crash on Russell Cave Road, a DUI incident on Nicholasville Road, and a head-on collision in Lexington County, S.C.

What are the details of the fatal crash on Interstate 64?

The crash on Interstate 64 occurred on Friday evening and involved four tractor-trailers and two cars, resulting in three fatalities. The westbound lanes were closed for hours during the investigation.

What actions are authorities taking regarding these crashes?

The Lexington Police Department and the Collision Reconstruction Unit are actively investigating the circumstances surrounding the crashes to assess causes and liabilities.

Key Features of Vehicle Crashes in Lexington Area

Date Location Injuries Fatalities Investigations
Friday Interstate 64 Multiple 3 Ongoing
Thursday Paris Pike 4 (2 critical) 0 Ongoing
Sunday Russell Cave Road 1 0 Closed
Saturday Nicholasville Road 3 (1 life-threatening) 0 Ongoing
Saturday Old Cherokee Road (S.C.) 1 (Driver injured) 1 Ongoing

Deeper Dive: News & Info About This Topic

HERE Resources

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Lexington Vehicle Crash Causes Road Closures
Kentucky State Police Enhance Road Safety for Labor Day Weekend
Head-On Collision Hospitalizes Two in Lexington
Three-Car Crash Disrupts Traffic on Alumni Drive in Lexington
Tragic Multi-Vehicle Accident on I-75 Claims Young Life
Cooper Drive to Close for Stormwater Improvement Project
Upcoming Lane Closures in Downtown Lexington for Resurfacing Work
Major Roadwork Scheduled in Lexington’s Downtown Area

Additional Resources

Lexington Area Experiences Series of Vehicle Crashes Resulting in Multiple Injuries and One Fatality

STAFF HERE LEXINGTON KY STAFF
Author: STAFF HERE LEXINGTON KY STAFF

The LEXINGTON STAFF WRITER represents the experienced team at HERELexingtonKY.com, your go-to source for actionable local news and information in Lexington, Fayette County, and beyond. Specializing in "news you can use," we cover essential topics like product reviews for personal and business needs, local business directories, politics, real estate trends, neighborhood insights, and state news affecting the area—with deep expertise drawn from years of dedicated reporting and strong community input, including local press releases and business updates. We deliver top reporting on high-value events such as Woodland Art Fair, Crave Food and Music Festival, and Railbird Festival. Our coverage extends to key organizations like Commerce Lexington and Blue Grass Community Foundation, plus leading businesses in education, manufacturing, and technology that power the local economy such as University of Kentucky, Toyota Motor Manufacturing, and Lexmark. As part of the broader HERE network, including HEREBowlingGreen.com and HERELouisville.com, we provide comprehensive, credible insights into Kentucky's dynamic landscape.

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